Functional polymorphisms in antioxidant genes in Hurthle cell thyroid neoplasm - an association of GPX1 polymorphism and recurrent Hurthle cell thyroid carcinoma
نویسندگان
چکیده
منابع مشابه
Functional polymorphisms in antioxidant genes in Hurthle cell thyroid neoplasm - an association of GPX1 polymorphism and recurrent Hurthle cell thyroid carcinoma
BACKGROUND Hurthle cells of the thyroid gland are very rich in mitochondria and oxidative enzymes. As a high level oxidative metabolism may lead to higher level of oxidative stress and can be associated with an increased risk for cancer, we investigated whether common functional polymorphisms in antioxidant genes (SOD2, CAT, GPX, GSTP1, GSTM1 and GSTT1) are associated with the development or cl...
متن کاملMolecular basis off hurthle cell papillary thyroid carcinoma.
Among thyroid neoplasms, Hurthle cell tumors (HCTs) have traditionally been a distinct diagnostic category. Hurthle cell adenomas are encapsulated follicular lesions with benign behavior. Hurthle cell carcinomas exhibit unequivocal capsular and/or vascular invasion; they are aggressive tumors with a poor prognosis. Recently, Hurthle cell papillary thyroid carcinomas (PTCs) have been identified ...
متن کاملGiant pedunculated esophageal liposarcoma associated with Hurthle cell thyroid neoplasia.
Giant pedunculated liposarcoma of the esophagus is considered a rare entity. They impose difficulties in management, especially the surgical approach. We report a case of giant pedunculated liposarcoma of the esophagus in a 62-year-old male who underwent cervical excision of this large tumor, and made a full recovery. Hurthle cell thyroid cancer was found during the work-up, which was managed a...
متن کاملIssues in Managing Hurthle Cell Carcinoma of Thyroid: A Case Report
A 61-year-old woman noticed a right neck lump in October 2001. Fine needle aspiration showed follicular neoplasm, adenoma versus carcinoma. The ultrasound scan showed a solid mass of maximum dimension of 3.7 cm. She had a right thyroid lobectomy and isthmectomy in January 2002 (first surgery). The tissue specimen showed a 4.5 cm Hurthle cell carcinoma (HCC) with vascular invasion. There were no...
متن کاملSuccessful treatment of Hurthle cell thyroid carcinoma with lung and liver metastasis using docetaxel and cisplatin.
A 36-year-old man was found to have Hurthle cell carcinoma, as diagnosed with surgical pathology after a lobectomy of the thyroid. A post-operative magnetic resonance imaging scan revealed a small mass in the lower pole of the right thyroid and a computed tomography scan showed bilateral nodules in the lungs and the neck, and multi-focal disease in the liver. He was treated with a docetaxel and...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Radiology and Oncology
سال: 2016
ISSN: 1581-3207
DOI: 10.1515/raon-2016-0031